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Cleanance Comedomed, an innovation from Laboratoires Eau Thermale Avène, fights spots and prevents them reappearing, with clinically proven effectiveness from seven days*. High tolerance for acne-prone skin.
Action rapide
Anti-récidive***
Haute tolérance
Sans parfum
Effectiveness demonstrated within 7 days*.
Fast-acting, prevents recurrence***, high tolerance
Usable by
Pregnant women - Young mothers - Teenagers - Adults
Age
From 12 year(s)
Skin type
Acne-prone skin
Need
Anti-imperfections - Anti recurrence
Made in France
Cleanance Comedomed, an innovation from Laboratoires Eau Thermale Avène has shown proven clinical effectiveness from seven days*, fights spots from the root with a unique action, and prevents them reappearing. Expert care for oily, acne-prone skin, Cleanance Comedomed is formulated using Comedoclastin™, a plant extract from the seeds of milk thistle. This active ingredient with patented properties** directly targets micro blackheads, reduces existing spots and blackheads and prevents new ones appearing. Cleanance Comedomed, applied twice a day, reduces spots within seven days* and provides clinically proven*** anti-recurrence action. Can be used by adults and teenagers from the age of 12. Non-comedogenic, high-tolerance* for acne-prone skin, its fast-absorbing, non-greasy texture leaves skin mattified. Cleanance Comedomed can be used alone, with other products, or after acne medication (excluding oral isotretinoin).
A few words from our expert
A formidable anti-imperfection treatment that acts on the submerged part of the spots for long-lasting clinical effectiveness on acne-prone skin.
Benefit
The revolutionary treatment for acne-prone skin that reduces spots within seven days* and limits their reappearance thanks to Comedoclastin™, a plant-based active ingredient extracted from Milk Thistle, with patented properties**
Benefits
• EFFECTIVENESS that is clinically proven. Reduces all types of acne-prone skin imperfections, thanks to Comedoclastin™** which acts at the root of spots to reduce them and limit them reappearing. Its light aqueous texture penetrates quickly, making it easier to apply, and leaves the skin supple, moisturised and mattified over time.
• FAST ACTION AND PREVENTS RECURRENCE : Cleanance Comedomed is clinically proven to reduce spots within seven days* and prevent recurrence***. For clearer skin and improved comfort every day.
• HIGH TOLERANCE : Cleanance Comedomed is highly tolerant*, whether used alone, in combination or in tandem with medical treatments (excluding oral isotretinoin). Its non-comedogenic formula is fragrance-free.
Texture benefit
A light, watery texture that is quickly absorbed and has a non-greasy finish that leaves the skin clean and matte.
Product scent
Fragrance-free
*Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days.
** Patent registered.
***International clinical observational study, 90% of patients without acne relapse at T6 months, (according to the definition of relapse in the GEA protocol ≥3 requiring the introduction of a drug treatment - oral or local), 48 subjects, two applications per day of Cleanance Comedomed for six months.
Biodegradable formula*
Formulated to limit the impact on the aquatic environment***
*According to a OECD 301 test or biodegradability index method
*** According to a OECD 301 test and CLP classification of the formula
Packaging
Fully recyclable packaging
Manufacturing
Formulated with one or more raw materials from the circular economy
Manufactured and packaged in an environmentally certified facility****
Cold-made formula without any heating
****According to ISO 14001 and/or 50001
Transportation
Low CO2 impact of raw material transport (< 70 g CO2 eq. )
Societal impact
Product manufactured and packaged in a factory with high social standards
Avene is a brand of the Pierre Fabre Group, certified at the highest Exemplary level of AFNOR Certification’s Committed to CSR and Responsibility Europe labels, thus consolidating a long-standing commitment to contributing to sustainable development.
Does ... not contain animal raw materials
Our commitments
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Frequency of use
2 times a day
Tips for use
Dispense 1 dose of Cleanance Comedomed on your fingertips.
• Start by dabbing it onto the T-zone and the cheeks.
• Use circular motions to boost penetration.
• Finish by smoothing on the cheeks and lower face.
Reapply morning and evening.
An expert tip
The 2 essential steps to take care of your oily, acne-prone skin!
Our one piece of advice:
• Rigorously yet gently remove make-up and cleanse the face, both morning and evening!
• Also apply an anti-blemish product morning and evening.
Clinical results
Effective for every oily,acne-prone skin type
7 daysreduces spots within 7 days¹
90%prevents recurrence for 90%²
45%reduced imperfections by -45% as of 2 months³, significant result versus control group
¹Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days.
²International observational clinical study, 90% of patients without acne relapse at T6 months, (according to the definition of relapse in the protocol GEA≥3 requiring the introduction of an oral or local drug treatment), 48 subjects, 2 applications per day of Cleanance Comedomed alone for 6 months.
³36 subjects with slight to moderate imperfections. Comparative clinical study (group treated twice/day N=18), control group (N=18) for 56 days.
AVENE THERMAL SPRING WATER (AVENE AQUA). ISOPROPYL ALCOHOL. PEG-6. GLYCERIN. SILYBUM MARIANUM FRUIT EXTRACT. SILICA. POLYACRYLATE-13. POLYISOBUTENE. POLYSORBATE 20. SORBITAN ISOSTEARATE. WATER (AQUA)
The consumer is advised to systematically check the composition of the product before purchasing it.
Avene thermal water
Thanks to a unique mineral and biological characteristic, it has soothing, repairing and rebalancing properties.
Comedoclastin™
Plant-based active ingredient with patented properties from Pierre Fabre Research. Milk thistle extract acts on epithelial cells reducing the formation of micro-comedones and preventing new spots.
FREQUENTLY ASKED QUESTIONS
Any concerns or questions? Our experts are here for you.
The smell is linked to the active ingredient Comedoclastin™ (milk thistle extract), which is present in the product at a dosage of 25%. This odour evaporates quickly and does not interfere with the tolerance of the product and does not present any risk to the skin. It has been proven that skin tolerates Cleanance Comedomed extremely well.
Yes, the start of an active treatment (whether a drug or dermo-cosmetic) can act as a trigger for a breakout. Under its effect, a large number of spots, previously dormant under the skin, emerge at the same time. This causes the phenomenon of a "flare-up" (an explosion or exacerbation of pimples). Treatment should be continued in all cases, because the next phase will allow for the rapid exhaustion of the "embryo stock” of spots.This will help to keep blemishes to a minimum. In case of discomfort, use can be reduced to once a day.
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